I did a little bit of a search but I couldn’t put my finger on the post that I think might want to know this. Between VR and other USB devices, I am pretty sure that someone here may be experiencing this:
TLDR: Zen 3 + Gen 4 GPU can generate USB dropouts (lose connectivity);
Yep, someone in my squadron has that problem with his Reverb G2, he fixed it with a PCIe USB card.
So far I haven’t noticed anything but I don’t have a VR headset (yet).
Apparently AMD have figured out what’s going on and have a BIOS update coming next month that should fix the issue.