For anyone wondering, @fearlessfrog’s guide still hold for the latest version of Ortho4XP (version 1.3.0), although there are a few differences.
For the rest of the post, I will document my minimalist attempt to get ‘better than default’ scenery into X-Plane with a minimum of effort 
For the Ortho4XP Python3 Script, you can find it here: Windows Binaries Dropbox Link. For updates, check the signature on the first post of this thread at the XPlane.org site;
I downloaded and installed according to the README.md text file. The Python3 install was easy and self explanatory, as were the steps to add the extra libraries. For this example I unzipped that archive in G:\Projects\Ortho4XP\bin;
Before yo go further, I recommend following this step from frog to get the HD/UDH Mesh tiles: X-Plane Ortho4XP Guide - #2 by BeachAV8R
I downloaded my tile zips to G:\Projects\Ortho4XP\Overlay\Earth_Nav_Data-zips:
And extracted the contents to:G:\Projects\Ortho4XP\Overlay\Earth nav data
On running the Ortho4XP app I was greeted with this screen:
And after futzing around, I found that clicking on the Globe icon was the place where I wanted to go to do the batch builds. Before you do that, click on the Tools icon (wrench and screwdriver) and set the path to your overlay tiles:
Note that you are putting the path to the location ‘above’ the ‘Earth nav data’ directory.
Now back to the Ortho4XP main window, click on that Globe icon and the Batch window looks like this:
Right click, hold and drag to move the map. Double click to select a single cell (Yellow box in the next picture, shift click to select multiple cells (the black boxes with the red dotted interior). Note the other places that I have already rendered. I have no idea why some of them show a denser dot pattern than the others. Select all the Batch build tiles options shown in the screenshot below to do all of the Step 1, Step 2, Step 2.5 and Step 3 parts that frog mentions in his main post above.
Click on that ‘Batch Build’ button and go back to the main Ortho4XP window to watch the output.
Once the process completes, you will have a series of tiles in your Orth4XP bin directory:
Copy these to your
Then get the overlays in there as well by copying the G:\Projects\Ortho4XP\bin\yOrtho4XP_Overlays to the X-Plane 11 Custom Scenery directory:
That was pretty much all I had to do to get ‘much better than the default’ X-Plane scenery.
The above screen shot is of CYFC Fredericton Airport after the update (but also with X-Plane.org CYFC scenery on top). I recognize all of the roads and features.
And that is a shot to the north west showing Fredericton in the distance. All the roads and features are where they should be
It is accurate enough to make out the glacier carved features of the landscape here. Awesome!
Also, while I am at it, once you get this scenery all created and added to X-Plane, it is a bit of a issue to remember what you have done. When you are adding new tiles, you do not want to re-render the old ones by mistake. I recommend the xOrgainizer app to help with that. It is easy to survey what X-Plane has installed. There is more functionality, but I have only started using it.
Here I have selected the scenery that I have rendered and added to X-Plane (the Canada folder which I enabled by making the red box turn green) and the OrbX Washington scenery.
